The town of Mezdra has a population of 12 000 inhabitants and lies at a distance of 14 km southeast of Vratza. Mezdra is the municipal centre of 27 settlements and a key junction station of the railway lines Sofia-Varna and Mezdra-Vidin. The town is situated amphitheatrically along the left bank of the Iskar River. On the territory of the municipality there are remains of a fortified prehistoric settlement and an ancient medieval fortress. The settlement is described in the Ottoman registry books in XV c. The municipality is specialized in the production of grains, fruits, vines and vegetables.

The tourist sights of the region are: the Cherepishki Monastery, The Strupetzki Monastery, the remains of the Kaleto fortress and the art gallery.